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相关概念视频

Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

88
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
88
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

227
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
227
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

145
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
145
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

68
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
68
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

449
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
449
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

173
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
173

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相关实验视频

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A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease
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儿科严格对克罗恩病进行治疗.

Alessandro Boscarelli1, Matteo Bramuzzo2

  • 1Department of Pediatric Surgery and Urology, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste 34137, Italy. alessandro.boscarelli@burlo.trieste.it.

World journal of gastroenterology
|April 15, 2024
PubMed
概括

儿科克罗恩病 (CD) 可能导致狭窄,需要进行干预. 目前的治疗方法具有很高的复发率,因此需要研究在儿童中严格治疗CD (SCD) 的新战略.

关键词:
克罗恩氏病是什么 克罗恩氏病是什么未来的前景 未来的前景洞察力 洞察力 见解 洞察力儿科 儿科 儿科严格的制 严格的制

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科学领域:

  • 儿科胃肠病学 儿科胃肠病学
  • 炎症性肠道疾病研究研究
  • 手术创新 在外科创新.

背景情况:

  • 克罗恩病 (Crohn's disease,简称CD) 是一种慢性消化道炎症状况,儿科发病率不断上升.
  • 大约25%的儿科CD病例会发展为严格的CD (SCD),往往需要干预.
  • 现有的非药物干预SCD包括内镜气球扩张,严格uroplasty和手术切除.

研究的目的:

  • 为了突出儿童严格治疗克罗恩病的管理方面的挑战.
  • 为了强调与儿童SCD相关的高复发率和终身手术风险.
  • 强调正在进行的关于改善儿科SCD结果的新策略的调查.

主要方法:

  • 审查当前的治疗策略,症状严格治疗CD.
  • 对儿科SCD患者的复发率和长期手术风险的分析.
  • 识别新兴的诊断和治疗方法.

主要成果:

  • 对于耐火性症状性SCD,经常需要进行非药物干预.
  • 紧张症表明,不论治疗方式如何,术后复发倾向.
  • 儿童SCD患者的终身手术风险在50%到90%之间.

结论:

  • 由于复发率高,儿童严格治疗克罗恩病带来了重大管理挑战.
  • 需要先进的诊断工具和最少侵入性的方法.
  • 新和新兴的策略对于改善儿科SCD患者的治疗结果和生活质量至关重要.