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特鲁索综合症与严重的视力损失作为最初的症状
Atsushi Okubo1, Ryo Obata2, Keiko Azuma2
1Ophthalmology, Saitama Red Cross Hospital, Saitama, JPN.
Cureus
|April 15, 2024
概括
特鲁索综合征是一种与癌症相关的高凝血性疾病,可导致视力丧失. 这种病例突出了它在胰腺癌患者的双边视力丧失和叶梗塞的呈现.
科学领域:
- 眼科医生 眼科 眼科
- 在瘤学瘤学.
- 血液学 血液学 血液学
背景情况:
- 特鲁索综合征是一种罕见的疾病,它将高凝血能力与恶性瘤联系起来.
- 它经常呈现出血栓事件,但视觉障碍较少报告.
- 早期诊断对于管理相关风险至关重要.
研究的目的:
- 报告一个特鲁索综合征病例,呈现双边视力丧失.
- 强调在患有视力衰退的癌症患者中考虑特鲁索综合征的重要性.
- 突出诊断方法和管理影响.
主要方法:
- 一个70岁的男性患有晚期胰腺癌的案例介绍.
- 眼科检查包括扩张眼底镜,OCT和ERG.
- 大脑MRI评估神经参与.
- 实验室测试凝结性标记物 (D-二聚体).
主要成果:
- 患者出现视力敏度下降,视网膜色素上皮缩,棉花斑,以及不正常的ERG.
- 大脑MRI揭示了脑叶梗塞.
- 升高的D-二次体证实了高凝血性,导致Trousseau综合征的诊断.
结论:
- 在癌症患者突然,深刻的视力丧失时,应该怀疑Trousseau综合征.
- 综合评估,包括神经成像和凝血研究是必不可少的.
- 及时诊断和管理可以减轻严重的并发症.
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