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含尼古丁产品对植入周围组织的影响:系统性审查和网络元分析
Orsolya Vámos1,2, Péter Komora2,3, Noémi Gede4
1Department of Prosthodontics, Semmelweis University, Budapest, Hungary.
概括
尼古丁产品的使用者,除了电子烟 (EC) 的使用者,与非吸烟者相比,表现出更糟糕的周植入健康状况. 欧洲共同体的使用者与非吸烟者有相似的结果,这表明不同尼古丁产品的风险各不相同.
科学领域:
- 口腔植入物学口腔植入物学
- 牙周病学 牙周病学
- 公共卫生 公共卫生
背景情况:
- 吸烟者患植入周病的风险更高.
- 这项研究比较了各种尼古丁产品用户的周围植入健康状况:电子烟 (EC),水管 (WP),香烟 (CS),无烟烟草 (ST) 和非吸烟者 (NS).
- 鉴于替代尼古丁产品日益流行,了解这些风险至关重要.
研究的目的:
- 系统地比较EC,WP,CS,ST和NS的使用者之间的围植特征.
- 评估不同尼古丁和烟草制品对边际骨损失 (MBL) 和其他周植入物参数的影响.
主要方法:
- 在四个数据库 (PubMed,EMBASE,Web of Science,CENTRAL) 进行系统的文献搜索,直到2023年4月.
- 包括39项观察性研究;32项通过贝叶斯网络元分析进行分析.
- 用MBL,探测口袋深度 (PPD),探测出血和炎症标记器提取数据;使用QUIPS和CINeMA评估的偏差风险和证据确定性.
主要成果:
- 非吸烟者表现出最少的边际骨损失 (MBL).
- 与非吸烟者相比,使用香烟 (CS),水管 (WP) 和无烟烟 (ST) 的人的MBL显著更高.
- 与非吸烟者相比,电子烟 (EC) 用户在MBL中没有显著差异;非吸烟者在二次结果中排名最高.
结论:
- 大多数含尼古丁产品的使用者,特别是CS,WP和ST,对植入周围组织健康有不利影响.
- 与非吸烟者相比,EC用户在许多周围植入物参数中没有显著差异.
- 对尼古丁产品使用者来说,患者教育,维护和戒烟支持至关重要;需要进一步进行直接比较的研究.
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