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Updated: Jun 13, 2026

Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair
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Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair

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在子模型中重建关键大小的下缺陷:通过充满细胞的3D打印水凝陶支架应用来增强血管生成和促进骨再生.

Seyyed Sajad Daneshi1, Lobat Tayebi2, Tahereh Talaei-Khozani3

  • 1Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz 71348, Iran.

ACS biomaterials science & engineering
|April 15, 2024
PubMed
概括

一个新的3D打印的脚手架结合纳米酸,β-三酸,原蛋白和人类牙纤维干细胞显著增强骨再生. 这种工程结构在关键大小的缺陷中促进骨质生成和血管生成.

关键词:
下缺陷是指下缺陷的情况.介质细胞干细胞介质细胞干细胞骨质发生过程 (osteogenesis)脚手架的设计设计.组织工程是组织工程.

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...