研究Lactobacillus plantarum涂有特雷梅拉多糖的研究,以改善其肠道粘附性
Yeli Zhu1, Fuhao Tang1, Yihan Wang1
1College of Light Industry and Food Engineering, Guangxi University, Nanning, China.
Journal of the science of food and agriculture
|April 15, 2024
概括
特雷梅拉多糖 (TPS) 显著增强了乳酸菌植物菌益生菌的肠道粘附性. 这项研究表明,TPS通过增加细菌对肠道细胞的附着性来促进益生菌功能.
科学领域:
- 微生物学 微生物学
- 生物材料科学 生物材料科学
- 食品科学 食品科学 食品科学
背景情况:
- 益生菌对肠道的粘附对于它们的有效性至关重要.
- 与类一起的特雷梅拉多糖 (TPS) 显示了益生菌封装和胃肠道保护的潜力.
研究的目的:
- 为了研究TPS (含类) 对益生菌的肠粘附的影响.
- 评估TPS在增强益生菌与肠道相互作用中的作用.
主要方法:
- 用不同比例的TPS和类素涂抹Lactobacillus plantarum.
- 冷干燥益生菌-多糖化合物混合物.
- 分析益生菌 - 菌素混合物的转生性质.
- 在实验室中评估L. plantarum与TPS作为碳源的Caco-2细胞的粘附.
- 进行全细胞蛋白质组分析以识别粘合蛋白.
主要成果:
- 益生菌-木素混合物表现出伪塑性流体特性,较高的TPS含量增加了粘度和产量应力.
- 在混合物中,TPS表现出粗性,符合赫歇尔-布克利模型.
- TPS显著增加了益生菌和粘菌之间的生物粘合力.
- 在实验室中,当TPS是唯一的碳来源而不是葡萄糖时,L. plantarum与Caco-2细胞的粘附率增加了228%.
- 在L. plantarum中,TPS促进了关键粘合蛋白的丰富性.
结论:
- 特雷梅拉多糖具有固有的益生菌性质.
- TPS有效地促进了Lactobacillus plantarum的肠粘附,增强了它的益生菌潜力.
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