适应性设计试验在饮食障碍研究:一个范围审查
Laura C Edney1, Mia L Pellizzer1,2
1Flinders University Institute for Mental Health and Wellbeing, Flinders University, Adelaide, South Australia, Australia.
The International journal of eating disorders
|April 15, 2024
概括
适应性设计试验为饮食障碍研究提供了有效的替代方案,但它们的使用是有限的. 这次审查确定了五项试验,突出了改善患者结果和试验效率的错失机会.
科学领域:
- 临床心理学 临床心理学
- 生物统计学 生物统计学
- 精神病学研究 精神病学研究
背景情况:
- 适应性设计试验是传统固定的试验设计的灵活和高效的替代方案.
- 尽管有优点,但适应性设计在饮食障碍研究中未得到充分利用.
研究的目的:
- 绘制适应性设计试验在饮食障碍研究中的应用现有文献.
- 确定该领域适应性试验的方法,结果和局限性.
主要方法:
- 在多个数据库 (Medline,Scopus,PsycInfo,Emcare,Econlit,CINAHL,ProQuest论文和论文) 中进行了系统的文献搜索.
- 研究包括使用适应性设计试验治疗饮食障碍的干预措施.
- 两个独立的审查员选引用和抽象数据.
主要成果:
- 确定了针对神经性厌食症,神经性食欲症和过度饮食障碍的五项适应性设计试验.
- 所有试验都采用了基于早期反应和预定义的停止规则的适应性治疗手臂切换.
- 没有研究包含信息分析或生活经验视角的价值.
结论:
- 饮食障碍试验中适应性设计的有限采用是提高试验效率,招聘,保留和结果的错失机会.
- 建议在未来的饮食障碍研究中实施适应性设计试验,解决操作和统计方面的考虑.
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