光学盘微血管性脱落在预周边性玻璃眼中
Min Hee Suh1, Robert N Weinreb2, Linda M Zangwill2
1Department of Ophthalmology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
Journal of glaucoma
|April 15, 2024
概括
视觉盘微血管性脱落 (MvD-D) 与更严重的前周周长玻璃眼有关. 在视野或视神经结构的变化显而易见之前,可能会出现这种早期的绿眼的迹象.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 微血管成像技术 微血管成像技术
背景情况:
- 预周度初级开角青光眼 (PPG) 呈现出诊断上的挑战.
- 光盘微血管性脱落 (MvD-D) 是一种潜在的青光斑损伤指标.
- 了解MvD-D与其他玻璃眼参数的关联对于早期检测至关重要.
研究的目的:
- 为了确定与光盘微血管性脱落 (MvD-D) 相关的因素,在患有前周度初级开角青光眼 (PPG) 的患者中.
主要方法:
- 光学连贯断层扫描血管学 (OCTA) 用于检测MvD-D在139个PPG眼睛.
- 分析的因素包括视野平均偏差 (MD),RNFL厚度,晶片膜 (LC) 缺陷,视觉盘出血,以及副状MvD-P.
- 眼睛与没有MvD-D之间进行了比较.
主要成果:
- 在49.6%的PPG眼中存在MvD-D.
- 与没有MvD-D的眼睛相比,MvD-D的眼睛显示RNFL更薄,VF MD更糟,焦点LC缺陷和MvD-P的患病率更高.
- 在多变量分析中,男性性别,更糟糕的VF MD,更薄的全球RNFL,焦点LC缺陷和MvD-P与MvD-D有显著的关联.
结论:
- 光盘微血管性脱落 (MvD-D) 与PPG中疾病严重程度的恶化有关.
- MvD-D经常发生在没有焦点膜膜缺陷或 parapapillary微血管性脱落的情况下.
- 视觉盘循环受损可能是前面的功能或结构变化的早期绿眼的迹象.
相关概念视频
01:25Glaucoma: Overview
560
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
560
01:27Open Angle Glaucoma: Treatment
440
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
440
01:20Anatomy of the Eyeball
7.1K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.1K