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Updated: Jun 28, 2025

Preparation of Formalin-fixed Paraffin-embedded Tissue Cores for both RNA and DNA Extraction
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阿尔法胎蛋白:过去,现在和未来

Yee Hui Yeo1, Yi-Te Lee1, Hsian-Rong Tseng2,3

  • 1Karsh Division of Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Hepatology communications
|April 15, 2024
PubMed
概括

阿尔法-胎蛋白 (AFP) 是肝癌 (HCC) 查,预后和治疗监测的关键生物标志物. 本综述详细介绍了AFP的发现,生物作用及其对临床实践及其未来HCC研究的影响.

科学领域:

  • 生物化学 生物化学
  • 免疫学 免疫学 免疫学
  • 在瘤学瘤学.

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背景情况:

  • 阿尔法-胎蛋白 (AFP) 是一种糖蛋白,在发育和怀孕期间对免疫调节至关重要.
  • 在产后,AFP基因转录被抑制,转移到专蛋白基因维护.
  • 产后AFP升高表明肝细胞受伤,再生或恶性转变.

结论:

  • AFP的实用性超越了生物标志物,在HCC中成为潜在的治疗点.
  • 了解AFP的作用可以提高HCC的管理和临床实践.
  • 讨论了HCC中AFP的未来研究方向.