在多重物质滥用妇女中,物质使用模式,数量和相关的风险因素
Nia Fogelman1, Marshall Tate1, Stephanie Wemm1
1Yale Stress Center, Yale University School of Medicine, New Haven, Connecticut, USA.
Addiction biology
|April 15, 2024
概括
多种物质使用 (PSU) 在女性中很常见,每天使用多种药物的比例很高. 压力和渴望,而不是疼痛或情绪,是这一群体中PSU的主要危险因素.
科学领域:
- 成 药物 药物 药物 药物
- 精神病学是一个精神病学.
- 妇女健康 妇女健康
背景情况:
- 多种物质使用 (PSU),定义为同时使用两个或两个以上的物质,由于增加了发病率和死亡率风险,这给公共卫生带来了重大挑战.
- 了解特定的PSU模式及其相关风险因素,特别是在女性等弱势群体中,对于开发有效干预至关重要.
研究的目的:
- 在经常使用可卡因,阿片类药物,大麻,酒精,二类药物和/或尼古丁的妇女中描述多物质使用模式.
- 调查压力/创伤,吸毒渴望,疼痛和焦虑/抑郁症状与女性多重物质使用指标之间的联系.
主要方法:
- 一项涉及94名女性 (19-65岁) 的横截面观察性研究,正在接受临床试验评估.
- 数据收集包括对压力/创伤性生活事件,药物渴望,疼痛评级和焦虑/抑郁症状的标准化调查.
- 描述了物质使用模式,包括多种物质的每日量和频率.
主要成果:
- 观察到每天使用多种物质的高患病率 (72.7%),与其他物质相比,阿片类药物的使用量很大.
- 增加压力/创伤事件的频率和更高的毒品渴望与累积的多物质使用日,数量和每日概率有显著的关联.
- 没有发现疼痛,焦虑和抑郁症状与多重物质使用指标有关.
结论:
- 在女性中存在特定的多物质使用模式,其特点是每天大量使用多种物质.
- 应激/创伤暴露和药物渴望的严重程度是与女性多重物质使用相关的重要危险因素.
- 针对压力/创伤管理和减轻渴望的干预措施可能有助于减轻女性多重物质使用风险.
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