ICTV病毒分类简介: 沙病毒类 2024年
Sotaro Chiba1, Nobuhiro Suzuki2, Leonardo Velasco3
1Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-0861, Japan.
The Journal of general virology
|April 15, 2024
概括
富沙病毒家族的特点是单片段,积极感应的RNA基因组. 这些病毒缺乏明显的病毒,具有独特的RNA指导的RNA聚合酶和RNA酶蛋白.
科学领域:
- 病毒学 病毒学
- 分子生物学分子生物学
- 纳税学是一种分类学.
背景情况:
- 沙病毒科 (Fusariviridae) 是一种具有单片段,正感RNA基因组的病毒家族.
- 基因组范围在5.9-10.7千基基底之间,通常是双基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基基
研究的目的:
- 总结国际病毒分类委员会 (ICTV) 关于Fusariviridae家族的报告.
- 提供Fusariviridae的基因组特征和独特特征的概述.
主要方法:
- 审查和综合ICTV报告中的信息.
- 基因组特征的分析,包括细分,感觉,大小和ORF.
主要成果:
- 富沙病毒群的基因组是单片段的,正感RNA,大小为5.9-10.7kb.
- 大多数基因组都是双的;5-近端ORF编码了RNA指导的RNA聚合酶 (RdRP) 和RNA酶 (Hel) 域.
- 沙病毒似乎不会形成病毒.
结论:
- 富沙病毒家族 (Fusariviridae) 是一个独特的病毒家族,具有独特的基因组和结构特征.
- 需要进一步的研究来了解二基斯特龙基因组中第二个ORF编码的蛋白质.
更多相关视频
相关概念视频
Retrovirus Life Cycles
45.9K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.9K
Retroviruses
12.2K
Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
12.2K
Viral Structure
62.2K
Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
62.2K
Viral Mutations
32.3K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
32.3K
Viral Recombination
23.4K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.4K
Non-LTR Retrotransposons
11.5K
As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
11.5K


