在现代医学中PLA的应用
Vincent DeStefano1, Salaar Khan1, Alonzo Tabada1
1Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794, USA.
Engineered regeneration
|April 15, 2024
概括
聚乳酸 (PLA) 是一种可再生资源的可生物降解生物聚合物. 它的多功能性使其非常适合医疗应用,包括个人防护设备 (PPE) 和医疗设备的3D打印.
科学领域:
- 生物材料科学 生物材料科学
- 聚合物化学 聚合物化学
- 生物技术是生物技术.
背景情况:
- 聚乳酸 (PLA) 是一种可生物降解和生物相容的聚合物,来自可再生资源.
- PLA的合成很简单,使其成为一种丰富且可持续的材料.
- 它的特性导致了各种生物医学领域的广泛研究.
研究的目的:
- 突出聚乳酸 (PLA) 作为生物材料的多样化应用.
- 强调PLA在3D打印中的重要性,特别是在医疗环境中.
- 讨论基于PLA的材料在先进医疗保健解决方案中的未来潜力.
主要方法:
- 关于聚乳酸 (PLA) 在医疗保健中的应用的文献综述.
- 分析PLA在组织工程,再生医学和医疗植入物中的作用.
- 检查PLA在医疗器械和个人防护设备 (PPE) 3D打印中的实用性.
主要成果:
- PLA被用于许多医疗应用,包括组织工程,心血管植入物,牙科材料,药物输送系统,骨科设备,癌症治疗和皮肤/肌愈合.
- 作为一种3D打印材料,PLA已被证明至关重要,特别是在COVID-19大流行期间,用于生产必不可少的PPE和呼吸机组件.
- 聚合物化学的进步不断扩大基于PLA的模式的有效性和应用.
结论:
- 聚乳酸 (PLA) 是一种高度通用的生物聚合物,在医疗保健领域具有显著的当前和未来潜力.
- PLA的生物降解性,可再生性和3D打印性使其成为医学创新的关键材料.
- 在聚合物化学领域的持续研究和开发将进一步加强PLA在解决医疗需求方面的作用.
相关概念视频
01:13Induced Pluripotent Stem Cells
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...
01:09Cytoskeletal Linker Proteins - Plakins
Plakins are large proteins with binding domains for microtubules, microfilaments, intermediate filaments, and membrane-associated protein complexes at cell junctions. Plakin functions are evolutionarily conserved and are primarily involved in organizing the different components of the cytoskeleton by crosslinking them to each other and connecting them to the cell-matrix and cell adhesion complexes. They are also known to interact with signal transducers, serve as scaffolds for signaling...
01:29Issues And Trends In Healthcare Delivery System
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
01:20Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors
Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
01:29Microorganisms in Medicine and Therapeutics
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
01:25Rapid Identification of Pathogens
MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...