[COVID-19重症患者的神经并发症]
M J Abenza-Abildúa1, M T Ramírez-Prieto2, R Moreno-Zabaleta2
1Sección de Neurología, Hospital Universitario Infanta Sofía, Madrid, España.
Neurologia (Barcelona, Spain)
|April 15, 2024
概括
在接受ICU治疗的严重COVID-19患者中,神经系统并发症很常见. 急性混综合征是普遍存在的,但得到了解决,而年龄较大与更长的ICU停留时间相关.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 临界护理医学 临界护理医学
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 感染可能导致严重疾病,需要进入重症监护室 (ICU).
- 在患有严重COVID-19的患者中,神经系统并发症越来越多.
- 了解这些并发症对于患者的管理和结果至关重要.
研究的目的:
- 分析入住ICU的重症SARS-CoV-2感染患者的神经复杂症的范围.
- 描述这些神经系统并发症的特征和结果.
- 为了确定患者因素和神经症状或ICU停留时间之间的潜在相关性.
主要方法:
- 进行了一项回顾性,观察性,描述性研究.
- 包括在2020年4月1日至6月30日期间因严重的SARS-CoV-2感染而入院于ICU的连续患者.
- 收集和分析了有关神经症状,诊断测试 (心血管,MRI,CT,EEG,EMG) 和ICU停留的数据.
主要成果:
- 分析了30名患有神经症状的患者. 最常见的疾病是急性混综合征 (93.33%) 和神经肌肉疾病 (50%).
- 在13.33%的患者中观察到脑血管疾病和脑病变/脑炎. 脑液分析通常是正常的 (20%),而神经成像显示了66.6%的变化.
- 高龄与更长的ICU停留时间有显著的相关性 (P=.002).
结论:
- 严重的COVID-19经常伴有神经复杂症,特别是急性混综合征和肌肉病变.
- 虽然急性混综合征通常会消失,但神经生理学和成像学发现并不总是与临床表现相关.
- 高龄是严重的COVID-19患者长期入院ICU的重要预测因素.
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