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Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

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Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
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  2. 应对查加斯心肌病的挑战和推进治疗策略
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  2. 应对查加斯心肌病的挑战和推进治疗策略

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应对查加斯心肌病的挑战和推进治疗策略

Mauro Felippe Felix Mediano1, Roberto Magalhães Saraiva2, Israel Molina3

  • 1Evandro Chagas National Institute of Infectious Diseases, Oswaldo Cruz Foundation, Rio de Janeiro, 21040-360, Brazil; Department of Research and Education, National Institute of Cardiology, Rio de Janeiro, Brazil.

Lancet (London, England)
|April 15, 2024
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No abstract available in PubMed .

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