反复性尿路感染患者的抗生素持续时间和尿路感染结果
Julia Shinnick1, Isabel Josephs2, Johanna A Suskin3
1From the Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Women and Infants Hospital/Warren Alpert Medical School of Brown University, Providence, RI.
Urogynecology (Philadelphia, Pa.)
|April 15, 2024
概括
对于患有复发性尿路感染 (rUTI) 的女性来说,针对急性尿路感染 (UTI) 的标准抗生素持续时间与延长持续时间一样有效. 这一发现支持当前针对该群体的急性尿路感染的指导方针一致的治疗方法.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 有限的证据表明,在有反复性尿路感染 (rUTI) 病史的妇女中,治疗急性尿路感染 (UTIs) 是有效的.
- 在RUTI患者中,急性尿路感染的最佳抗生素治疗持续时间尚不清楚.
研究的目的:
- 为了比较与指导方针一致的抗生素治疗效果与延长的抗生素治疗时间,以治疗女性的急性尿路感染.
- 为了确定较短的抗生素疗程是否会导致更高的持续性,复发或复发率.
主要方法:
- 从2016年到2020年,对219名患有RUTI的女性进行了回顾性非劣势性研究.
- 用指南一致的治疗治疗急性尿路感染的结果与延长抗生素持续时间的结果进行比较.
- 结果包括尿路感染的持续/复发或4周内复发.
主要成果:
- 分析了553种急性尿路感染; 47%的患者接受了符合指南的抗生素持续时间.
- 15.6%的尿路感染持续或复发,5.2%的尿路感染复发.
- 持久性/复发或复发率与延长的持续时间相比,与指导方针一致的持续时间 (4.4%的差异) 不逊色.
结论:
- 针对急性尿路感染的指导方针一致的抗生素持续时间与RUTI妇女的长时间持续时间不逊色.
- 支持在这个患者群体中用于急性尿路感染的标准抗生素治疗长度.
- 可能有助于优化抗生素的使用,并减少不必要的长期治疗.
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