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(生物) 可降解聚生物材料的基于寡头的分子标签

Joanna Rydz¹, Khadar Duale², Wanda Sikorska²

¹Centre of Polymer and Carbon Materials, Polish Academy of Sciences, M. Curie-Skłodowskiej 34, 41-800 Zabrze, Poland; Department of Food, Agricultural and Biological Engineering, The Ohio State University, Wooster 44691, OH, United States.

International journal of biological macromolecules

|April 15, 2024

概括

这项研究引入了一种绿色方法,将生产年信息嵌入到可生物降解的聚合物中,使用寡. 这些存储的数据即使在聚合物消失后仍然可以检索.

科学领域:

材料科学材料科学材料科学
聚合物化学聚合物化学
生物技术是生物技术.

背景情况:

医疗行业对环保功能材料的需求日益增长.
对标记可生物降解聚合物的兴趣,以追踪它们的环境命运.
需要在聚合物矩阵中存储信息的方法.

研究的目的:

开发一种绿色方法,用于生物降解聚合物中的信息存储.
将生产年数据编码为使用寡的聚乙酸 (PLLA) 和聚乙烯基酸-co-1,4-丁二甲酸/聚乙酸 (PBAT/PLA) 薄膜.
评估存储信息在生物降解之前和之后的稳定性和可检索性.

主要方法:

在PLLA和PBAT/PLA聚合物薄膜中加入寡 (PEP).
编码二进制信息 (生产年) 作为氨基酸序列在寡.
使用质谱学解码信息.
在工业堆肥过程中研究薄膜的特性和稳定性.
使用MRC-5哺乳动物纤维细胞进行MTT测定.

主要成果:

在聚合物薄膜上成功编码和解码生产年信息.
证明了橄类的稳定性,允许在生物降解前后检索信息.
标记有生物降解的聚合物薄膜的特征.
使用哺乳动物纤维细胞对PLLA和PLLA/PBAT进行初始MTT研究.

结论:

建立了一种简单的绿色方法,用于将信息存储在可生物降解的聚合物中.
基于寡的系统允许持久的信息编码和检索.
开发的材料对需要可追溯性和环境监测的应用具有前景.

关键词:

标识识别识别识别标签标签标签标签标签大分子信息存储的信息存储.这是一种类.聚1,4-丁酸盐-共1,4-丁二甲酸盐) 是一种聚是一种聚.聚氨酸是一种多氨酸.

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