立陶宛的C型肝炎查:第一年的结果和实现世卫组织消除目标的情景
Janina Petkevičienė1,2, Alexis Voeller3, Eglė Čiupkevičienė4
1Health Research Institute, Faculty of Public Health, Lithuanian University of Health Sciences, Tilžės str. 18, LT47181, Kaunas, Lithuania. janina.petkeviciene@lsmu.lt.
BMC public health
|April 15, 2024
概括
立陶宛 立陶宛 立陶宛
科学领域:
- 肝病学和传染病流行病学.
- 公共卫生干预和查计划
- 病毒性型肝炎 (HCV) 消除策略
背景情况:
- 世界卫生组织 (WHO) 设定了到2030年消除C型肝炎的目标.
- 立陶宛于2022年5月启动了一项国家HCV查计划.
- 该计划鼓励全科医生在特定人群中进行HCV检测.
研究的目的:
- 模拟立陶宛目前的C型肝炎流行病状况.
- 用第一年查数据评估世卫组织消除目标的进展情况.
- 确定到2030年实现HCV消除的要求.
主要方法:
- 使用马尔科夫病进展模型.
- 分析了国家健康保险基金对查,诊断和治疗患者的数据.
- 包括常规GP访问进行抗HCV查和积极病例的专家转诊.
主要成果:
- 超过79万个人进行了查,其抗HCV阳性率为1.5% (11,943).
- 男性的血清发病率 (1.9%) 比女性 (1.2%) 高.
- 建模表明需要2180次额外的年度治疗,并扩大纤维化限制,以达到世卫组织的目标.
结论:
- 查的第一年达到44%的目标人群.
- 如果不增加治疗和放松纤维化限制,立陶宛不太可能实现2030年消除目标.
- 实施消除策略可以防止每年1000例新感染,并挽救150人的生命.
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