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Updated: Jun 28, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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干扰素α刺激DEXH盒酶58,以防止肝细胞铁化

Kai-Wei Jia1, Ren-Qi Yao2,3, Yi-Wen Fan1

  • 1National Key Laboratory of Medical Immunology & Institute of Immunology, Naval Medical University, Shanghai, 200433, China.

Military Medical Research
|April 15, 2024
PubMed
概括

干扰素-α (IFN-α) 刺激DExH盒酶58 (DHX58) 来增强谷氨过氧化酶4 (GPX4) 的转化,防止肝脏缺血/再输液 (I/R) 损伤中的铁亡. 这一发现表明IFN-α是肝脏I/R损伤的潜在治疗方法.

关键词:
DExH盒子化酶58 (DHX58) 的使用葡萄氨酸过氧化酶4 (GPX4) 的作用.缺血/再输液 (I/R) 的情况含有2 (YTHDC2) 的YT521-B同源域.m6A 修改的修改

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