在甲状腺眼睛疾病中,中心和外周对比度敏感性.
Kasturi Bhattacharjee1, Obaidur Rehman2, Parul Ichhpujani3
1Department of Ophthalmic Plastic and Reconstructive Surgery and Oculofacial Aesthetics, Sri Sankaradeva Nethralaya, Guwahati, Assam, India.
Indian journal of ophthalmology
|April 16, 2024
概括
对比度敏感性 (CS) 测试显示在甲状腺眼病 (TED) 中视觉功能受损,即使视力敏度正常. 周围的CS会随着炎症和双甲状腺视神经病变 (DON) 而恶化,有助于早期的DON诊断.
科学领域:
- 眼科医生 眼科 眼科
- 神经眼科 神经眼科
- 医疗成像医学成像
背景情况:
- 甲状腺眼病 (TED) 可以影响视觉功能,有时是微妙的.
- 甲状腺视神经病变 (DON) 是TED的一个视力威胁的并发症.
- 评估超越标准视觉敏度的视觉功能对于早期发现TED并发症至关重要.
研究的目的:
- 在患有甲状腺眼病 (TED) 的患者中评估中心和外周对比度敏感性 (CS).
- 为了在TED患者中比较CS与非甲状腺视神经病变 (DON) 的患者.
- 在TED中确定疾病活动和CS之间的关系.
主要方法:
- 横截面研究比较了18名TED患者 (33只眼睛) 与18名健康对照.
- 眼科检查包括视力敏度,眼内压力和裂纹灯生物显微镜.
- 使用Spaeth-Richman对比敏感性测试评估的中央和外围对比敏感性 (CS).
主要成果:
- 与对照组相比,TED患者的中央和总CS显著减少 (P < 0.001).
- 在DON眼睛和非DON眼睛中,在中央和外围区域观察到显著的CS缺陷 (P <0.05).
- 在四个区域中的三个区域 (P <0.05) 中,增加的临床活性得分与减少的外周CS相关.
结论:
- 对比敏感性测试在TED中检测到视力障碍,即使视力敏度正常.
- 周围神经系统损伤与炎症增加和DON相关.
- 串行CS监测可能有助于早期诊断DON.
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