红细胞输血的特点在中国的非常早产婴儿中
Lu Zheng1, Xinyue Gu2, Pu Zhao3
1Department of Neonatology, Children's Hospital of Fudan University, Shanghai, China.
Vox sanguinis
|April 16, 2024
概括
红细胞输血在中国非常早产婴儿中很常见,病例在医院之间有很大差异. 这种高的输血率与严重并发症和死亡风险的增加有关.
科学领域:
- 新生儿医学 新生儿医学
- 儿科血液学 儿科血液学
- 临床结果研究研究
背景情况:
- 关于中国非常早产婴儿 (VPI) 红血细胞 (RBC) 输血实践和结果的国家数据有限.
- 了解输血模式对于改善对这一脆弱群体的护理至关重要.
研究的目的:
- 描述中国VPI中红细胞输血的发生率和变化.
- 确定红细胞输血和VPI中的临床结果之间的关联.
主要方法:
- 一项队列研究涉及13,447名在2019年至2020年期间在中国70家三级医院入院的VPI.
- 通过中国新生儿网络 (CHNN) 收集的数据包括输血率,时间和关键新生儿发病率.
主要成果:
- 超过一半 (52.2%) 的VPI接受了至少一次红细胞输血,平均每婴儿2次输血.
- 输血率在NICU (13.5%-95.0%) 之间有显著差异,在重症婴儿中更高.
- 红细胞输血与死亡,严重腹腔内出血,NEC/SIP,败血症,BPD,严重ROP和cPVL的患病率增加有关.
结论:
- 这项研究提供了中国VPI中红细胞输血的第一个基线数据,揭示了惊人的高率和实质性的跨站点可变性.
- 建议紧急制定针对VPI的红细胞输血的国家指导方针,以标准化护理和改善结果.
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