牙和发育缺陷的牙在脑:一个元分析
Thaynara Nascimento de Oliveira1, Victor Zanetti Drumond2, José Alcides Almeida de Arruda3
1School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Oral diseases
|April 16, 2024
概括
患有脑 (CP) 的人与没有CP的人相比,牙损伤或牙面膜发育缺陷 (DDE) 没有显著差异. 这一发现是基于对现有研究的系统审查和元分析.
科学领域:
- 口腔健康研究 口腔健康研究
- 公共卫生 公共卫生
- 儿科牙科 儿科牙科
背景情况:
- 大脑 (CP) 由于运动,感官和认知障碍,会影响口腔健康.
- 了解CP患者牙损伤和牙发展缺陷 (DDE) 的患病率对于有针对性的干预至关重要.
研究的目的:
- 系统地审查和元分析患有或没有CP的个体的牙损伤和DDE的发生情况.
- 为了比较这两个群体之间的口腔健康结果.
主要方法:
- 搜索了五个数据库和灰色文献,寻找相关研究.
- 使用RStudio进行随机效应模型元分析,将结果呈现为平均差异 (MD) 和几率比率 (OR) 与95%置信区间 (CI).
- 使用纽卡斯尔-太华尺度评估偏差风险,使用GRADE评估证据确定性.
主要成果:
- 包括25项与59,997名参与者的研究;12项用于元分析.
- 没有发现有或没有CP的个体之间的DMFT,dmft,DMFS,dmfs或DDE的显著差异.
- 调查结果的证据确定性被评估为非常低.
结论:
- 与非CP同龄人相比,患有CP的个人不会表现出明显不同的牙损伤或DDE率.
- 需要进一步研究以更高的证据确定性来证实这些发现.
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