老年人的抑郁症状和认知能力下降
Malcolm Forbes1, Mojtaba Lotfaliany2, Mohammadreza Mohebbi1
1The Institute for Mental and Physical Health and Clinical Translation (IMPACT), Deakin University, Geelong, VIC, Australia.
International psychogeriatrics
|April 16, 2024
概括
晚年抑郁的轨迹会影响老年人的认知功能. 新兴和持续的抑郁症与处理速度和记忆力的下降有关.
科学领域:
- 老年学和认知神经科学
- 精神病学和心理健康研究研究
- 纵向衰老研究 纵向衰老研究
背景情况:
- 很少有研究研究了晚年抑郁轨迹对不同认知领域的具体影响.
- 了解这些关系对于开发针对老年人群认知衰退的有针对性的干预措施至关重要.
研究的目的:
- 确定抑郁症状的不同轨迹如何影响老年人特定的认知功能.
- 为了区分各种抑郁模式的认知影响,随着时间的推移.
主要方法:
- 一项前性纵向队列研究,涉及澳大利亚和美国的11,035名社区老年人 (平均年龄75岁).
- 每年使用流行病学研究中心抑郁症量表10 (CES-D-10) 评估抑郁症症状,确定四种轨迹:非抑郁,下值,持久和新出现的抑郁症.
- 认知功能包括全球认知 (3MS),口头流利 (COWAT),处理速度 (SDMT) 和情节性记忆 (HVLT-R) 在平均2年内进行了评估.
主要成果:
- 新兴抑郁症与处理速度 (SDMT),情节性记忆 (HVLT-R),全球认知 (3MS) 和复合分数的性能受损有关.
- 持久性抑郁症与处理速度 (SDMT) 和全球认知 (3MS) 和复合分数的缺陷有关.
- 低于值的压力与受损的处理速度 (SDMT) 和复合分数有很小的关联.
结论:
- 抑郁症状,特别是新出现和持续的轨迹,与老年人处理速度和其他认知领域的晚期损害有关.
- 确定的抑郁轨迹对认知功能有不同的影响,尽管观察到的影响通常很小.
- 这些发现强调了在评估衰老中的认知健康时考虑抑郁症状随时间变化的重要性.
更多相关视频
相关概念视频
01:30Negative and Cognitive Symptoms of Schizophrenia
48
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
48
01:30Cognitive Development During Adulthood
94
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
94
01:27Depressive Disorders: MDD and Dysthymia
112
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
112
01:18Depression: Overview
242
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
242
01:26Alzheimer's Disease: Overview
468
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
468
01:30Dementia
113
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
113