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铜 (II) 酸作为一种电催化电极,用于阴极检测尿三甲

Pachanuporn Sunon^1,2, Busarakham Ngokpho¹, Keerakit Kaewket¹

¹School of Chemistry, Institute of Science, Suranaree University of Technology, 111 University Avenue, Suranaree, Muang, Nakhon Ratchasima 30000, Thailand. kamonwad@g.sut.ac.th.

|April 16, 2024

概括

我们开发了一种使用铜(II) 酸 (CuPc) 电极的新托检测方法. 这种电化学传感器在生物样本中提供了敏感和选择性的托测量,克服了干扰问题.

科学领域:

电化学电化学电化学
分析化学分析化学
生物感应是一种生物感应.

背景情况:

检测体液中的托芬对于诊断各种健康状况至关重要.
现有的方法经常遭受干扰,限制准确性.
电化学方法为敏感和选择性分析物检测提供了潜力.

研究的目的:

开发一种新的电化学传感器,用于敏感和选择性地检测托.
为了克服与传统的托氧化方法相关的干扰问题.
在生物样本中验证传感器的性能.

主要方法:

使用铜(II) 酸 (CuPc) 改性电极进行电化学检测.
研究了通过还原反应检测托.
进行了线性回归分析,以确定度依赖的电流响应.
计算了检测极限 (LOD) 和传感器可重现性.

主要成果:

该CuPc电极通过还原机制实现了二的检测.
在两个度范围 (0.0013-0.10毫米和0.10-1.20毫米) 中观察到线性反应.
获得了高灵敏度 (14.7 ± 0.5 μA mM−1 和 3.5 ± 0.1 μA mM−1) 和低的 LOD (0.39 μM).
传感器显示出出色的可重复性 (<5% RSD) 和尿样中的高回收率 (101 ± 4%).

结论:

开发的基于CuPc的电化学传感器提供了一种强大而灵敏的托检测方法.
这种方法有效地减轻了其他检测技术中存在的干扰问题.
该传感器在临床诊断和生物流体分析中的实际应用方面显示出显著的希望.

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