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在肝脏和/或脏功能障碍患者中对聚米辛B的种群药动力学模型进行系统评估

Xueyong Li1,2, Yu Cheng1, Bingqing Zhang1,2

  • 1Department of Pharmacy, Fujian Medical University Union Hospital, 29 Xin Quan Rd, Fuzhou, 350001, Fujian, People's Republic of China.

Journal of pharmacokinetics and pharmacodynamics
|April 16, 2024
PubMed
概括

已建立的聚米辛B (PMB) 种群药动力学 (PopPK) 模型缺乏外部预测能力,特别是在器官功能障碍患者中. 贝叶斯预测显示,通过先前的数据来提高PMB剂量准确度是有前途的.

关键词:
外部评价 外部评价功能障碍 功能障碍 功能障碍肝脏功能障碍 肝脏功能障碍波利米克辛B是一种多重的物质.人口的药理动力学.

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