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Updated: Jun 28, 2025

Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis
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Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis

Published on: December 5, 2017

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在循环林E1过度表达细胞中,基因组稳定性需要RAD52依赖的线粒DNA合成

Anastasia Audrey1, Yannick P Kok1, Shibo Yu2

  • 1Department of Medical Oncology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713GZ Groningen, the Netherlands.

Cell reports
|April 16, 2024
PubMed
概括

环素E1的过度表达会导致DNA损伤,这种损伤会持续到线粒分裂. 依赖RAD52的线粒DNA合成 (MiDAS) 修复这些病变,但其抑制降低了癌细胞的活力.

关键词:
在CCNE1中,科普:分子生物学 分子生物学在米达斯的中间.在RAD52中使用RAD52.破裂诱导的复制.乳腺癌 乳腺癌 乳腺癌细胞循环中的细胞循环.环 E1 E1 环 E1 环 E1 环发生线粒分裂 (mitosis).在基因上,我们发现了基因上的差异.复制压力是复制的压力.

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