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在脑静脉血栓症患者中,与静脉附带因素相关的因素
Phirat Petchprom1, Nuttha Sanghan2, Rujimas Khumthong2
1Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla, Thailand.
PloS one
|April 16, 2024
概括
在25.3%的泰国脑静脉血栓症患者中存在静脉附带体. 顶部斜鼻封闭和荷尔蒙暴露是与静脉附带相关的独立因素.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 血管医学 血管医学
背景情况:
- 大脑静脉血栓形成 (CVT) 是一种罕见但严重的疾病.
- 静脉附带体在大脑的静脉排水中起着至关重要的作用.
- 在CVT中确定与静脉附带因素相关的因素对于了解疾病病理生理学和预后很重要.
研究的目的:
- 确定与泰国诊断为脑静脉血栓症的患者静脉附带体存在相关的因素.
- 为了确定这种患者队列中静脉附带病的患病率.
主要方法:
- 一项对被诊断患有CVT的患者进行了20年后期的队列研究.
- 从电子医疗记录中收集的数据.
- 由两名神经放射学家使用库雷希分类来评估静脉附带物.
- 进行单变量和多变量逻辑回归分析以确定相关因素.
主要成果:
- 在79名CVT患者中,静脉附带病的患病率为25.3%.
- 患有静脉附带病的患者年轻,更有可能患上较高的斜鼻封闭和荷尔蒙暴露.
- 多变量分析确定了上部斜鼻封闭 (aOR 3.581) 和荷尔蒙暴露 (aOR 7.276) 作为与静脉附带相关的独立因素.
结论:
- 大约有四分之一的泰国CVT患者有静脉附带体.
- 上部斜鼻的封闭和荷尔蒙暴露独立地与CVT中静脉附带的发展有关.
- 这些发现有助于理解CVT中的补偿机制.
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