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功能性SYNTAX评分的可行性和诊断性能来源于动态CT心肌 perfusion成像的动态CT心肌 perfusion成像

Xu Dai¹, Lihua Yu¹, Yarong Yu¹

¹Departments of Radiology (X.D., L.Y., Y.Y., Wenli Yang, Z.L., J.Y., J.Z.), Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China.

Circulation. Cardiovascular imaging

|April 16, 2024

概括

动态CT心肌输液成像 (CT-MPI) 有效计算功能SYNTAX得分 (FSS_CT-MPI),显示与侵入性FSS的强烈一致. 这种非侵入性方法可以准确地对多血管冠状动脉疾病患者进行分类,特别是那些严重化的患者.

科学领域:

心血管成像 - 心血管成像
干预心脏病学干预心脏病学
放射学放射学是一门学科.

背景情况:

计算机断层扫描 (CT) 分数流量储备 (FFR) 衍生功能SYNTAX得分 (FSS_CT-FFR) 帮助多血管冠状动脉疾病的治疗决策.
动态CT心肌输液成像 (CT-MPI) 提供优越的诊断准确性比CT-FFR用于识别血液动力学显著的冠状动脉疾病.

研究的目的:

评估CT-MPI衍生功能SYNTAX得分 (FSS_CT-MPI) 的可行性.
将FSS_CT-MPI与侵入性FSS进行比较,以确定风险分层的准确性.

主要方法:

对119名多血管冠状动脉疾病患者的回顾性分析.
侵入性FSS (FSS_侵入性) 与非侵入性FSS_CT-MPI和FSS_CT-FFR的比较.
对FSS_CT-MPI与FSS_侵入性的一致性评估 (加权 κ) 和重新分类 (NRI).

主要成果:

在FSS_CT-MPI和FSS_侵入性风险分类之间达成良好一致 (加权 κ = 0.808).
FSS_CT-MPI显示了患者的显著重新分类 (NRI = 0.30,P<0.001).
在严重化病例中,FSS_CT-MPI与FSS_CT-FFR相比显示出更高的诊断价值 (AUC为0.976比0.884).

结论:

来自CT-MPI的非侵入性FSS是可行的,并且与侵入性FSS高度一致.
在多血管冠状动脉疾病中,CT-MPI能够准确地对FSS进行分类,特别是在严重化的患者中.

关键词:

计算机断层扫描血管图谱冠状动脉疾病是一种冠状动脉疾病.分数流量储备,心肌组织血液动力学血液动力学心肌 perfusion 影像成像,用于心肌 perfusion 的成像.

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