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Updated: Jun 28, 2025

A Scalable, Cell-Based Method for the Functional Assessment of Ube3a Variants
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AlphaFun:基于结构对齐的蛋白质组注释揭示了为什么功能不明的蛋白质 (uPE1) 是如此之少的研究.

Hengxin Pan1, Zhenqi Wu1, Wanting Liu1

  • 1MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.

Journal of proteome research
|April 16, 2024
PubMed
概括

研究人员开发了AlphaFun,这是一种使用深度学习预测结构的新型蛋白质功能注释策略. 这种方法成功地注释了99%的人类蛋白质组,包括以前没有注释的蛋白质,进步了蛋白质组的理解.

关键词:
功能性注释 功能性注释功能分布的功能分布是什么基因本体学预测预测uPE1PE1 的使用情况.

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