极大的带有更高的恶性瘤或并发症风险吗? 一个病例控制研究研究
Chen Hazout1, Aviv Daniel1, Oren Ziv1
1Department of Otolaryngology Head and Neck Surgery, Soroka University Medical Center, Israel; Faculty of Health sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.
American journal of otolaryngology
|April 16, 2024
概括
甲状腺的大小不会增加手术并发症或恶性瘤的风险. 然而,整体差异化甲状腺癌的发病率为17%,因此需要仔细考虑切除.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 病理学 病理学 病理学
背景情况:
- 甲状腺的定义尚不清楚,但大小可能会影响恶性瘤和手术并发症的发生率.
- 评估甲状腺的大小对患者结果的影响对于临床管理至关重要.
研究的目的:
- 调查甲状腺的大小与恶性瘤和术后并发症的发生率之间的关系.
- 为了澄清甲状腺切除术决策中子大小的临床意义.
主要方法:
- 在2015-2023年期间,对144次甲状腺切除 (叶片≥4厘米) 的回顾性分析.
- 被分类为大 (4-8厘米) 和极大 (≥8厘米);瘤<1厘米被排除在恶性瘤评估之外.
- 收集的数据:人口统计,细胞学,组织学和术后并发症.
主要成果:
- 极大子表现出增加气管狭窄的趋势 (45%对23%).
- 整体差异化甲状腺癌 (DTC) 发生率为17%,子大小没有显著差异.
- 结节性增生在极大子中更频繁 (73%对53%);各组之间的并发症率相似.
结论:
- 甲状腺的大小不是增加手术并发症或恶性瘤的独立风险因素.
- 显著的17%的差异化甲状腺癌率强调了考虑切除所有子的重要性.
- 管理策略应考虑到恶性瘤的潜力,无论子的大小如何.
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