大动脉置换的部分或完整椎切除 - 多中心研究
Nora Goebel1, Tomasz Stankowski2, Francesco Pollari3
1Robert-Bosch-Krankenhaus GmbH, Stuttgart, Baden-Wuerttemberg, Germany.
The Thoracic and cardiovascular surgeon
|April 16, 2024
概括
动脉置换的部分上椎切除术显示了与完成椎切除术相比较的重大不良事件. 然而,最少的侵入性方法提供了更短的ICU停留时间和更低的再住院率.
科学领域:
- 心血管外科心血管外科
- 最少侵入性的技术
- 大动脉门的更换
背景情况:
- 微创心脏手术的比较好处尚未得到充分证实.
- 通过部分上椎切除术 (PUS) 和完全中椎切除术 (MS) 进行的外科动脉置换 (SAVR) 结果需要评估.
研究的目的:
- 为了比较使用PUS和MS的SAVR的短期和中期结果.
- 评估微创性SAVR的安全性和有效性.
主要方法:
- 一项大型的德国多中心队列研究包括了2,929名患者,他们在2016-2020年期间接受了孤立SAVR.
- 倾向性得分匹配创建了一个由1990名患者组成的队列进行分析.
- 主要终点:主要不良心脏和脑血管事件 (MACCE) 在30天和5年的随访.
主要成果:
- 未调整的MACCE率在PUS下较低,但在倾向性得分匹配后没有统计学意义 (30天:3.9%PUS对5.4%MS;5年:9.9%PUS对11.3%MS).
- 在PUS组显著缩短了重症监护室 (ICU) 停留时间,减少了德雷斯勒综合征病例,并降低了再住院率.
- 在3.8%的PUS病例中,转换为全胸腔切除术发生.
结论:
- 通过部分上椎切除和完整中椎切除的外科动脉置换产生可比的MACCE率.
- 部分上椎切除与改善的结果有关,包括更短的ICU停留时间和更低的德雷斯勒综合征和再住院率.
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