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基于计算机断层扫描的身体构成与老年肺移植接受者的术后发病率有关

Daria Kifjak^1,2, Helmut Prosch¹, Stefan Schwarz³

¹Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Wien, Wien, Austria.

The Thoracic and cardiovascular surgeon

|April 16, 2024

概括

CT扫描可以评估老年肺移植 (LTx) 候选人的身体储备. 肌肉量低,脂肪量高的患者在LTx后面临更高的并发症风险和更长的住院时间.

科学领域:

医学成像医学成像
移植手术是一种移植手术.
老年医学老年医学

背景情况:

在老年患者中,有限的身体储备是肺移植 (LTx) 的禁忌.
在这个人群中评估身体储备对于手术候选人至关重要.
计算机断层扫描 (CT) 提供了定量评估的潜力.

研究的目的:

在老年肺移植候选人中建立基于CT的物理储备量化.
为了将CT衍生的身体组成与外科手术期间的结果相关联.

主要方法:

对60岁以上接受LTx.的患者进行了回顾性研究.
在移植前的CT扫描中,半自动测量中间骨脂肪和背部肌肉区域.
测量标准化和与临床参数的相关性.

主要成果:

患者根据肌肉和脂肪成分 (肌肉高脂肪,肌肉低脂肪,其他) 进行分类.
较低肌肉脂肪高的组显示伤口感染和气管切除风险显著增加.
此组还经历了长时间的ICU和住院,以及LTx后的更长的通风时间.

结论:

移植前CT衍生体构可以识别具有更高风险的老年LTx候选人.
这些参数可以预测更糟糕的术后结果,帮助临床决策.

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