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功能疗法和腺切除术临床试验,用于II类恶性闭塞 (FACT-II):随机对照试验的协议
Feiyang Guo1,2, Chenxing Lv1,2, Bojun Tang1,2
1State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
BMJ open
|April 16, 2024
概括
这项研究比较了腺切除术 (T&A) 之后的双块治疗 (TB) 与结核病治疗之后的T&A 在患有阻塞性睡眠呼吸暂停 (OSA) 和II类缺陷的儿童中. T&A手术的时间影响了OSA患者的正牙治疗的有效性.
科学领域:
- 牙科 牙科是指牙科的专业.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 睡眠医学 睡眠医学
背景情况:
- 在儿科阻塞性睡眠呼吸暂停 (OSA) 中,二级缺陷与下逆转是常见的,通常与横向大缺陷有关.
- 腺突增大 (AHT) 是小儿OSA的主要原因,可能会恶化睡眠呼吸障碍并影响正牙治疗的稳定性.
- 双块 (TB) 器件用于早期正义牙,但它们的有效性可能会因AHT诱导的变化而受到影响.
研究的目的:
- 调查腺切除术 (T&A) 手术时间对双块 (TB) 功能治疗的疗效和稳定性的影响.
- 为了评估患有II级下逆转和AHT诱导的OSA的儿童的治疗结果.
主要方法:
- 一个单中心,并行组,优势随机对照试验,涉及40名年龄在8-14岁的患者.
- 参与者被随机分配到T&A,其次是结核病治疗或结核病治疗,其次是T&A.
- 主要结局包括呼吸暂停-呼吸暂停指数和A-nasion-B角度的变化;次要结局评估牙,骨,呼吸道和生活质量的变化.
主要成果:
- 该部分尚未提供,因为该研究是拟议的.
结论:
- 这项研究旨在确定T&A手术与结核病治疗相结合的最佳时机,以改善特定缺陷的儿科OSA患者的治疗结果.
- 这些发现将指导临床实践,指导该患者群体进行手术和正牙干预的顺序.
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