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Updated: Jun 28, 2025

A Syngeneic Orthotopic Osteosarcoma Sprague Dawley Rat Model with Amputation to Control Metastasis Rate
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通过增强CD44的稳定性,POLE2促进骨髓瘤的进展

Baichuan Wang1, Hongzhi Hu1, Xiaohui Wang2

  • 1Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan, 430022, China.

Cell death discovery
|April 16, 2024
PubMed
概括

DNA聚合酶epsilon 2 (POLE2) 通过增加CD44表达和激活Rac信号来促进骨髓瘤 (OS) 的进展. 准POLE2和CD44为这种骨癌提供了潜在的新疗法.

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