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Updated: Jun 28, 2025

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通过Cas2和AcrVA5之间的直接相互作用来抑制原体细胞集成的洞察力

Mingfang Bi1, Wenjing Su1, Jiafu Li1

  • 1College of Veterinary Medicine, Jilin University, 130062, Changchun, Jilin, China.

Nature communications
|April 16, 2024
PubMed
概括

一种抗CRISPR蛋白,AcrVA5,通过乙化Cas2.2来抑制CRISPR-Cas间隔器的获取. 这种乙化阻止了原体细胞的集成,并为CRISPR-Cas生物学提供了新的见解.

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