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在童年虐待和同龄人受害中,异常的大脑结构连接和社会认知
Lena Lim1,2, Lia Talozzi3, Henrietta Howells4
1Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. Lena.lim@kcl.ac.uk.
BMC psychiatry
|April 16, 2024
概括
儿童时期的压力来自照顾者和同龄人的影响大脑通路不同. 这些神经变化可能会影响社会认知,特别是情感理解.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
背景情况:
- 儿童虐待与神经生物学变化和社会认知缺陷有关.
- 同龄人受害 (PV) 是另一种常见的早期压力因素,神经效应研究较少.
- 这项研究研究了CM和PV引起的神经通道改变及其与情感思维理论 (ToM) 的关系.
研究的目的:
- 检查童年人际关系压力 (CM和PV) 与大脑白质管道异常之间的关联.
- 探索这些神经变化与情感思维理论 (ToM) 之间的关系.
主要方法:
- 107名健康年轻人 (34名CM,35名PV,38名对照) 接受了通道图和基于全脑通道的空间统计 (TBSS).
- 分析的重点是分数异构性 (FA) 和组织之间的管道体积差异.
- 评估了神经指标和情绪虐待和情感ToM的措施之间的相关性.
主要成果:
- 在CM组中,在边缘和身体状通路中,包括右侧未切割囊中,表现出更高的FA.
- CM与较小的右前胸膜辐射 (ATR) 通道体积和较高的左ATR FA有关,这与情绪虐待和增强的情感ToM有关.
- 在PV组中,在下面的前后囊中表现出较低的FA,与减少的情感ToM相关.
结论:
- 从照顾者和同龄人的早期生活压力不同地影响连接额叶,叶和叶皮层的神经通路.
- 这些独特的神经变化可能是不典型的社会认知的基础,包括情感性ToM.
- 研究结果强调了不同类型的早期人际关系压力的特定神经生物学影响.
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