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平均血小板体积与牙周炎有关:一个横截面研究
Chenying Zhou1,2, Ye Liu1,2, Jingjing Bai1,2
1School of Stomatology, Zunyi Medical University, Zunyi, Guizhou, China.
BMC oral health
|April 16, 2024
概括
较高的平均血小板体积 (MPV) 与牙周炎的风险增加有关. 这项研究发现,在美国成年人中,MPV水平升高与中度至重度牙周病之间存在显著联系.
科学领域:
- 牙周病学 牙周病学
- 血液学 血液学 血液学
- 公共卫生 公共卫生
背景情况:
- 平均血小板体积 (MPV) 和牙周炎之间的关系尚不清楚.
- 牙周炎是一种普遍的口腔疾病,具有全身健康影响.
研究的目的:
- 在美国成年人中调查MPV水平与中度/重度牙周炎之间的关联.
- 探索这种关系中的潜在改变因素.
主要方法:
- 来自NHANES 2009-2012数据集的6809名参与者的分析.
- 使用自动分析仪测量MPV,根据CDC/AAP标准对牙周炎进行诊断.
- 应用多重逻辑回归,平滑曲线拟合,子组分析和相互作用测试.
主要成果:
- 在较高的MPV水平和中度/重度牙周炎 (OR=1.090,P=0.01211) 之间发现了显著的积极关联.
- 在最高MPV三位数的个体有21.6%更大的牙周炎的概率比最低三位数 (OR=1.216,P=0.00816) 相比.
- 在特定的子组中观察到积极的关联,包括60岁以下,低收入,肥胖或高血压.
结论:
- 平均血小板体积水平与美国成年人口的牙周病相关.
- 升高的MPV可能是牙周炎风险的潜在指标或因素.
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