视觉和药物治疗后的结果 横侧鼻腔支架 对于异常发病性内高血压
Armin Handzic1, Jim Shenchu Xie, Eef Hendriks
1Faculty of Medicine (AH, JM, EM), Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Michael G. DeGroote School of Medicine (JSX), McMaster University, Hamilton, Canada; Faculty of Medicine (EH, PM, PN), Division of Neuroradiology, Department of Medical Imaging, University of Toronto, Toronto, Canada; Faculty of Medicine (JM, EM), Division of Neurology, Department of Medicine, University of Toronto, Toronto, Canada; and Kensington Vision and Research Center (JM), Toronto, Canada.
概括
横侧鼻腔支架 (TSS) 有效治疗异常性内高血压 (IIH),使大多数患者能够停止服用内压力 (ICP) 降低药物并改善视觉功能.
科学领域:
- 神经外科 神经外科
- 眼科医生 眼科 眼科
- 神经学 神经学
背景情况:
- 异常性内高血压 (IIH) 经常被用横侧鼻腔支架 (TSS) 治疗.
- 对IIH的TSS后视觉和药物治疗结果存在有限的神经眼科数据.
- 这项研究评估了IIH患者在TSS后的视觉结果和药物断奶.
研究的目的:
- 为了评估IIH患者接受TSS的视觉结果.
- 为了确定TSS后ICP降低药物的停用率.
- 评估TSS在IIH管理中的安全性和有效性.
主要方法:
- 对15名接受了TSS的IIH患者 (2016-2022) 的回顾性审查.
- 收集关于人口统计,症状,视觉功能和药物治疗的数据.
- 配对威尔科克森测试比较了支架前和后的视力敏度 (VA) 和视野平均偏差 (VFMD).
主要成果:
- 所有15名患者在TSS后表现出症状和 papilledema 改善.
- 10名患者停止服用ICP降低药物,4名患者降低了剂量.
- VFMD在造血栓后显著改善 (P < 0.001);VA变化没有显著意义.
- 没有发生缩或血栓形成;没有需要进一步的手术.
结论:
- 对于IIH患者来说,TSS是一种安全有效的治疗方法,这些患者有严重的症状或药物问题.
- 大多数患者可以在TSS后停止使用ICP降低药物.
- 在IIH中,TSS导致症状和视觉功能的显著改善.
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