Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

ATP and Macromolecule Synthesis01:28

ATP and Macromolecule Synthesis

5.6K
Biological macromolecules are organic compounds, predominantly composed of carbon atoms. The carbon atoms are covalently bonded with hydrogen, oxygen, nitrogen, and other minor elements. There are four major biological macromolecule classes: carbohydrates, lipids, proteins, and nucleic acids.
Most macromolecules are composed of single subunits, or building blocks, called monomers. The monomers combine with each other using covalent bonds to form larger molecules known as polymers.
Conversion of...
5.6K
Polymers02:34

Polymers

35.7K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
35.7K
Ribozymes02:47

Ribozymes

12.3K
The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower eukaryotes. Ribozymes were first discovered in 1982 when Tom Cech’s laboratory observed Group I introns acting as enzymes. This was shortly followed by the discovery of another ribozyme, Ribonulcease P, by Sid Altman’s laboratory. Both Cech and Altman received the Nobel Prize in chemistry in 1989 for their work on ribozymes.
Ribozymes can...
12.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

3D-Printed Milli-Fluidic Mixing-Extrusion Platform for Continuous, High-Throughput LNP Production.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Direct imaging-based gradient metasurface sensor enabling spectrometer-free ultrasensitive biomolecule detection.

Nature communications·2026
Same author

3D printing of droplet microfluidic devices: principles, wetting control, scale-up, and beyond.

Lab on a chip·2026
Same author

Photo-Cross-Linkable Polysaccharide-Based Multilayered Films for Durable Micropatterned Antifogging Surfaces.

Chem & bio engineering·2025
Same author

Low-Surface-Energy Capped Hydrogel Micropillar Arrays for Transparent Superhydrophobic Antifogging Surfaces.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

Slippery Behavior of PEGylated Surfaces.

ACS applied materials & interfaces·2025

相关实验视频

Updated: Jun 28, 2025

Forming Giant-sized Polymersomes Using Gel-assisted Rehydration
08:45

Forming Giant-sized Polymersomes Using Gel-assisted Rehydration

Published on: May 26, 2016

9.4K

可编程的酶反应网络在人造细胞类聚合体中

Hanjin Seo1, Hyomin Lee1

  • 1Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk, 37673, South Korea.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|April 17, 2024
PubMed
概括

这项研究使用滴滴微流体来制造具有可控制酶反应的合成细胞. 这些人造细胞可以模仿细胞通信,并形成复杂的社区空间时间生物信息.

科学领域:

  • 合成生物学 合成生物学
  • 生物化学 生物化学
  • 材料科学 材料科学 材料科学

背景情况:

  • 精确控制体外酶反应对于自下而上的人工细胞设计至关重要.
  • 目前的方法缺乏用于复杂,多层次的生物信息的膜结合区.
  • 设计更高阶的人工细胞群落仍然是一个挑战.

研究的目的:

  • 开发一种用于合成细胞中酶反应的时空控制的方法.
  • 设计能够模仿细胞通信的人工细胞群体.
  • 在合成细胞中创建失衡系统.

主要方法:

  • 使用滴滴微流体来合成具有可调节分子透性的聚合体.
  • 实施竞争逆酶反应来控制基质的可用性.
  • 利用差异膜透性进行选择性分子传输.

主要成果:

  • 在聚合物体内证明了燃料驱动的子微分区的形成.
  • 使用外部信号和燃料实现了酶反应的时空控制.
  • 成功构建了一个可编程的酶反应网络,模仿细胞通信.

结论:

关键词:
人工细胞的人工细胞.细胞与细胞之间的通信.协类动物 协类微流体学 在微流体学方面一些聚合物的聚合物.

更多相关视频

OaAEP1-Mediated Enzymatic Synthesis and Immobilization of Polymerized Protein for Single-Molecule Force Spectroscopy
08:34

OaAEP1-Mediated Enzymatic Synthesis and Immobilization of Polymerized Protein for Single-Molecule Force Spectroscopy

Published on: February 5, 2020

6.7K
Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer
09:37

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer

Published on: April 27, 2020

11.0K

相关实验视频

Last Updated: Jun 28, 2025

Forming Giant-sized Polymersomes Using Gel-assisted Rehydration
08:45

Forming Giant-sized Polymersomes Using Gel-assisted Rehydration

Published on: May 26, 2016

9.4K
OaAEP1-Mediated Enzymatic Synthesis and Immobilization of Polymerized Protein for Single-Molecule Force Spectroscopy
08:34

OaAEP1-Mediated Enzymatic Synthesis and Immobilization of Polymerized Protein for Single-Molecule Force Spectroscopy

Published on: February 5, 2020

6.7K
Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer
09:37

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer

Published on: April 27, 2020

11.0K
  • 滴滴微流体能够创建复杂的人工细胞社区.
  • 具有明显透性的聚合体能够精确控制酶反应.
  • 这一平台有助于重建时空生物信息和细胞通信.