主体内共感染相互作用对主体间寄生虫传播动态的影响因空间尺度而异
Shaun P Keegan1, Amy B Pedersen2, Andy Fenton1
1Department of Evolution, Ecology and Behaviour, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 7ZB, UK.
Proceedings. Biological sciences
|April 17, 2024
概括
寄生虫共感染会影响疾病,但也会改变寄生虫的传播. 这项研究表明,木鼠中胃肠道寄生虫之间的负面相互作用会影响局部传播,而不是广泛传播.
科学领域:
- 生态学和进化生物学
- 寄生虫学的寄生虫学
- 疾病生态学 疾病生态学
背景情况:
- 同感染寄生虫之间的宿主内部相互作用会影响个体感染结果.
- 这些相互作用对宿主寄生虫传播和空间尺度之间的影响基本上是未知的.
- 之前的研究在木鼠中发现了线虫Heligmosomoides polygyrus和虫Eimeria hungaryensis之间的负面相互作用.
研究的目的:
- 研究宿主内部寄生虫相互作用如何影响宿主之间的传播动态.
- 确定这些传输效应运行的空间尺度.
- 评估共感染相互作用对匈牙利埃梅里亚和埃梅里亚虫传染的影响.
主要方法:
- 开发和应用一种新的空间显式分析.
- 利用了来自野生森林老鼠 (Apodemus sylvaticus) 群体的寄生虫感染数据.
- 比较了Eimeria hungaryensis (与H. polygyrus相互作用) 和Eimeria apionodes (与H. polygyrus不相互作用) 的传播动态.
主要成果:
- 宿主内部H. polygyrus和E. hungaryensis之间的负面相互作用显著改变了E. hungaryensis的传播.
- 这种传播的变化仅在受感染宿主周围的局部区域内观察到.
- 没有检测到E. apionodes对传播的影响,它与H. polygyrus没有强烈的相互作用,在任何空间尺度上.
结论:
- 宿主内部的共感染相互作用可以扩展到宿主之外,以影响寄生虫传播动态.
- 这些效应在空间上受到限制,在与寄生虫传播相关的局部尺度上运作.
- 针对一个寄生虫的药物治疗可能会对非目标共感染寄生虫的传播产生意想不到的影响.
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