低瘦身量与肥胖的一致性,使用不同的定义,以及与高尿素血的相关性
Huan Xiao1, Longxiangfeng Hu1, Mengyu Xie1
1Department of Radiology, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, China.
Frontiers in nutrition
|April 17, 2024
概括
肥胖的低肌肉质量 (LLM) 与高尿血的风险更高有关. 这项研究发现,在诊断LLM与肥胖症方面存在中度至强度的一致性,强调其与增加的超尿血症风险的关联.
科学领域:
- 代谢健康 代谢健康
- 身体组成分析分析.
- 流行病学 流行病学
背景情况:
- 标识形肥胖症缺乏共识.
- 萨科佩尼性肥胖症和高尿血症之间的联系尚未得到充分证实.
研究的目的:
- 评估低瘦质量 (LLM) 与肥胖定义的一致性.
- 为了研究LLM与肥胖和高尿血症风险之间的相关性.
主要方法:
- 利用了25252名参与国家健康和营养检查调查 (1999-2018) 的数据.
- 定义了肥胖的LLM,使用尾肌肉量与BMI比率的比率,结合BMI,身体脂肪百分比 (BF%),或腰围 (WC).
- 采用科恩的kappa进行协议分析和后勤回归,用于高尿素血风险评估.
主要成果:
- 在肥胖定义中,LLM与肥胖的流行率从6.6%到10.1%不等,显示中度到强度的一致.
- 患有LLM或任何肥胖定义的个体患有高尿血的几率明显更高.
- 结合LLM和肥胖症,与健康个体相比,高尿血症的风险增加了2.44至3.12倍.
结论:
- 对LLM与肥胖的诊断一致性在所有定义中都很好,尽管发病率低.
- 结合肥胖的LLM与显著增加的高尿路血症风险有关.
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