对肺癌患者的住院结局,患者呈现上静脉血栓症
Jay Vakil1, Ekrem Turk1, Maria Cristina Cuartas-Mesa1
1Department of Medicine, Cook County Health, Chicago, IL, USA.
概括
上腔静脉 (SVC) 血栓形成是肺癌患者罕见的并发症. 这种情况增加了住院,成本和死亡率,并指出了种族差异.
科学领域:
- 在瘤学瘤学.
- 血管医学 血管医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 上腔静脉综合征 (SVC) 是一种影响胸部主要静脉的疾病,可由SVC血栓形成引起.
- SVC血栓形成是癌症患者的罕见但已知的并发症.
- 在肺癌患者中早期检测和管理SVC血栓形成可能会改善结果并降低医疗保健费用.
研究的目的:
- 调查肺癌患者中SVC血栓形成的种族和社会经济差异.
- 分析 SVC 血栓形成对肺癌患者住院时间,住院费用和死亡率的影响.
主要方法:
- 利用了肺癌患者国家住院样本的数据.
- 肺癌患者与没有SVC血栓形成之间的结果比较.
- 使用STATA进行统计分析.
主要成果:
- 在肺癌住院患者的0.15% (480,750例中720例) 中存在SVC血栓形成.
- 患有SVC血栓形成的患者住院时间更长 (10天而不是6天),费用更高 (117,320美元而不是80,806美元).
- SVC血栓形成显著增加住院患者的死亡风险 (18.0%与7.7%相比),非白人种族与较高的死亡率相关.
结论:
- SVC血栓形成是肺癌患者显著的负面预后因素.
- 种族,保险和并发症影响肺癌中SVC血栓的发展.
- 需要进一步的研究来解决已发现的医疗保健差异.
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