Enterococcus faecium菌株AK_C_05的完整基因组序列,具有适用于畜牧业的潜在特征
Hyunok Doo1, Jin Ho Cho2, Minho Song3
1Department of Animal Biotechnology, Dankook University, Cheonan 31116, Korea.
Journal of animal science and technology
|April 17, 2024
概括
我们测序了从韩国食物中分离出来的Enterococcus faecium菌株AK_C_05的基因组. 这种细菌使用特定的酶有效地代谢碳水化合物,突出其独特的代谢能力.
科学领域:
- 微生物学 微生物学
- 基因组学就是基因组学.
- 食品科学 食品科学 食品科学
背景情况:
- 菌 (Enterococcus faecium,简称E. faecium) 是一种在各种环境中常见的细菌.
- 传统的韩国发酵大豆食品Cheonggukjang是新型微生物菌株的潜在来源.
- 了解发酵食品中的E. faecium菌株的基因组特征可以揭示独特的代谢特性.
研究的目的:
- 为了呈现Enterococcus faecium菌株AK_C_05的完整基因组序列.
- 为了确定负责这种菌株中碳水化合物代谢的基因.
- 分析从各种碳水化合物中产生能源的基因组潜力.
主要方法:
- 对E. faecium菌株AK_C_05.05的隔离和全基因组测序
- 基因组组装和注释以识别基因及其功能.
- 使用正统组集群 (COG) 的比较基因组分析.
主要成果:
- 完整的基因组由一个染色体 (2,691,319 bp) 和一个质粒 (177,732 bp) 组成.
- 标注揭示了2827个蛋白质编码序列,18个rRNA和68个tRNA.
- 鉴定了编码alpha-galactosidase,beta-glucosidase和alpha-L-arabinofuranosidase的基因,这表明碳水化合物的有效利用.
结论:
- 菌菌株AK_C_05具有独特的基因组,具有全面碳水化合物代谢的基因.
- 这种菌株专注于碳水化合物运输和新陈代谢,可以从各种碳水化合物来源产生能量.
- 这些基因组信息提供了关于E. faecium在发酵食品环境中的功能能力的见解.
相关概念视频
Microorganisms in Agriculture and Food industry
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
Stringent Response in E. coli
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Clinical Significance of Antibiotic Resistance
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...


