关于eugenol和2-phenylphenol功能化sol-gel涂料的抗菌特性和耐久性
Ana Suárez-Vega1, Gemma Berriozabal1, Juan Perez de Iriarte1
1TECNALIA, Basque Research and Technology Alliance (BRTA), Mikeletegi Pasealekua 2, Donostia-San Sebastián, Spain.
Heliyon
|April 17, 2024
概括
新的sol-gel涂层包含eugenol和2-phenylphenol显示抗菌活性对抗细菌和病毒. 虽然有效,但需要进一步改进,以提高这些更安全的表面消毒解决方案的长期耐用性.
科学领域:
- 材料科学 材料科学 材料科学
- 表面化学 表面化学
- 微生物学 微生物学
背景情况:
- 公共空间的微生物表面污染是一个重大问题,化学消毒剂对健康和环境构成风险.
- 开发更安全,更有效的抗微生物表面对于公共卫生和环境可持续性至关重要.
- 索尔凝涂层为开发先进的抗菌材料提供了一个有前途的平台.
研究的目的:
- 为了评估含有生物制剂的sol-gel涂层的抗菌疗效和耐久性.
- 调查欧原醇和2-烯作为抗菌涂料中的活性剂的潜力.
- 评估这些新型涂料配方的安全性和耐用性.
主要方法:
- 使用氧化物路径与酸催化物的sol-gel合成,以创建混合-titania-methacrylate矩阵.
- 将欧原醇 (复合剂和杀菌剂) 和2- (ECHA批准的杀菌剂) 纳入涂料配方中.
- 使用29Si NMR,ATR-FTIR,形状测量,纳米印记和三角学试验进行表征.
主要成果:
- 索尔凝涂层显示,已证实抗菌作用,对抗阳性 (金黄色葡萄球菌) 和阴性细菌 (大肠杆菌).
- 这些涂料表现出非细胞毒性和显著的杀菌活性.
- 鉴定证实了涂料的化学成分,厚度,机械性能和初始功效.
结论:
- 经过测试的sol-gel涂层有效地提供了抗微生物表面特性.
- 欧原醇和2-烯是可在sol-gel矩阵中加入的可行的生物制剂.
- 进一步开发是必要的,以提高在操作条件下抗微生物效应的耐用性.
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