对用于透析的中央静脉导管的评估与血流感染相关
Erwin Hadi Chandra1,2, Tom Ch Adriani1, Ahmadi Alwi1
1Division for Vascular and Endovascular, Department of Surgery, Faculty of Medicine, Hasanuddin University, Dr. Tadjuddin Chalid National Hospital, Makassar, Indonesia.
Annals of vascular diseases
|April 17, 2024
概括
导管相关的血流感染 (CRBSI) 在血液透析 (HD) 患者中很常见. 格拉姆阳性细菌,特别是金黄色葡萄球菌,是最常见的罪祸首,对氨基糖化物表现出敏感性.
科学领域:
- 传染性疾病 传染性疾病
- 腎臟病學 (nephrology) 是一種醫學.
- 临床微生物学 临床微生物学
背景情况:
- 导管相关的血流感染 (CRBSI) 是血液透析 (HD) 中的一个重大挑战.
- 中枢静脉导管 (CVC) 对于末期病 (ESRD) 患者的紧急HD接入至关重要.
- 了解CRBSIs的微生物环境对于有效管理至关重要.
研究的目的:
- 为了识别导致CHD患者CRBSI的常见病原体.
- 确定这些病原体的抗生素敏感性模式.
- 探索 CRBSI 的潜在预测因素.
主要方法:
- 对患有HD CRBSI的成年ESRD患者的回顾性分析.
- 进行了血液培养和敏感性测试.
- 纳入标准侧重于患者需要紧急的HD通过CVC感染.
主要成果:
- 鉴定出了格拉姆阳性微生物 (57.5%) 和格拉姆阴性生物 (42.5%).
- 黄金葡萄球菌是最常见的病原体 (30%),其次是Pseudomonas aeruginosa (20%).
- 黄金菌对氨基糖化物和类素表现出敏感性,而P. aeruginosa对第三代素敏感.
结论:
- 使用超过两周的非道化CVC会增加CRBSI风险.
- 甲素和红细胞沉积率可以预测CRBSIs.
- 格拉姆阳性细菌主导CRBSIs,大多数菌株对氨基糖化物敏感.
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