了解癌症临床试验参与的财务成本
Courtney P Williams1, Luqin Deng1, Nicole E Caston1
1University of Alabama at Birmingham, Birmingham, Alabama, USA.
Cancer medicine
|April 17, 2024
概括
癌症临床试验中近一半的患者经历了经济困难,主要是由于旅行费用. 这种财务负担减少了加入未来试验的意愿,突出了需要支持性干预的需要.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 患者倡导 患者倡导
背景情况:
- 标准的癌症治疗通常会导致经济困难.
- 对于癌症临床试验参与者的自付费用,人们的了解有限.
- 这项研究调查了参与癌症临床试验的财务影响.
研究的目的:
- 探索与参与癌症临床试验相关的财务影响和自付费用.
- 确定导致试验参与者经济困难的因素.
- 评估经济困难对未来临床试验参与意愿的影响.
主要方法:
- 从2022年12月到2023年5月期间收集的美国癌症成年人的横截面调查数据.
- 对参与癌症临床试验,与试验相关的财务困难和社会人口统计数据的调查答案的分析.
- 描述性统计,Cramer's V用于关联大小,以及调整后相对风险 (aRR) 的修改Poisson回归.
主要成果:
- 在650名受访者中,有18%参与了癌症临床试验;其中47%的人报告了经济困难.
- 与审判相关的财务困难与失业/残疾和更长的旅行距离 (>1小时) 有关.
- 主要支出包括旅行费 (71%),医疗费 (58%),餐费 (40%) 和住房费 (40%). 受访者每月需要200-1000美元.
- 51%的人因困难而不愿意参加未来的试验;13%的人因成本而拒绝参加试验.
结论:
- 经济困难显著影响近一半的癌症临床试验参与者,主要是由旅行费用驱动的.
- 干预对于减轻财务负担和潜在提高癌症临床试验参与率至关重要.
- 解决成本障碍对于通过临床试验公平获得新型癌症疗法至关重要.
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