慢性淋巴细胞白血病的治疗坚持和不良事件管理:未来的挑战和战略

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Maurlia D Upchurch¹, Benyam Muluneh¹

¹Department of Pharmacology and Therapeutics, UNC Chapel Hill, Chapel Hill, NC, USA.

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概括

口服抗癌剂 (OAAs) 将慢性淋巴细胞白血病 (CLL) 治疗转移到家庭,这带来了坚持挑战. 本文概述了一种结构化的方法,用于识别和克服最佳患者结果的障碍.

科学领域:

在瘤学瘤学.
血液学血液学血液学
药理学药理学是指药理学的学科.

背景情况:

慢性淋巴细胞白血病 (CLL) 治疗已经转向口服抗癌药物 (OAA).
这种过渡带来了诸如不遵守,副作用和财务毒性等挑战.
解决这些障碍对于有效的家庭CLL管理至关重要.

研究的目的:

讨论一种结构化的方法来识别和解决CLL患者最佳治疗结果的障碍.
检查影响OAAs患者的坚持维度.
提出预防和管理治疗障碍的策略.

主要方法:

利用世界卫生组织的五个维度的坚持:治疗,卫生系统,与病情相关的,社会/经济因素和患者因素.
分析这些领域在CLL患者中如何表现.
讨论跨治疗阶段的预防和管理策略.

主要成果:

在CLL患者中确定OAA遵守的关键障碍.
基于世卫组织的维度来解决遵守问题的框架.
强调个性化的解决方案,以应对患者特定的挑战.

结论:

一个多学科的计划是支持OAAs的CLL患者的必要条件.
涉及药剂师,社会工作者,护士,高级从业者和医生,确保全面的护理.
结构化识别和个性化干预是克服障碍和改善结果的关键.

关键词:

坚持的坚持坚持的坚持 BTK 抑制剂的使用在 CLL CLL 中.口服瘤消毒药是什么意思有针对性的治疗.维尼托克莱克斯 (Venetoclax) 是一个

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