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Updated: Jun 28, 2025

Functional Assessment of BRCA1 variants using CRISPR-Mediated Base Editors
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Published on: February 28, 2021

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对于患有BRCA1/2致病变体的健康妇女的决策指导 随机对照EDCP-BRCA试验的结果

Stephanie Stock1, Anna Isselhard, Arim Shukri

  • 1Faculty of Medicine, University of Cologne and Institute for Health Economics and Clinical Epidemiology, Cologne; Faculty of Medicine, University of Cologne and Center for Familial Breast and Ovarian Cancer, University Hospital Cologne; Faculty of Medicine, University of Cologne and Institute for Health Economics and Clinical Epidemiology, Cologne; Institute for Public Health and Healthcare Research, University of Bremen; Institute for Human Genetics, University Hospital Heidelberg; Department of Obstetrics and Gynecology, Rechts der Isar Hospital Technical University of Munich; Schumpeter School of Business and Economics, Competence Center for Health Economics and Healthcare Research, University of Wuppertal; Department of Obstetrics and Gynecology, Carl Gustav Carus University Hospital, Dresden; Faculty of Medicine, University of Cologne and Center for Familial Breast and Ovarian Cancer, University Hospital Cologne; Institute for Health and Healthcare Science, Martin Luther University of Halle-Wittenberg, Halle (Saale); Department of Obstetrics and Gynecology, University Hospital Schleswig-Holstein, Kiel; Faculty of Medicine, University of Cologne and Department of Psychosomatics and Psychotherapy, University Hospital Cologne; Department of Psychosomatic Medicine, Robert Bosch Hospital, Stuttgart; Department of Obstetrics and Gynecology, University Hospital Würzburg.

Deutsches Arzteblatt international
|April 17, 2024
PubMed
概括

一个决策指导计划帮助BRCA1/2致病变体 (PV) 的妇女在预防性护理决策中发挥更积极的作用. 虽然决策角色的一致性没有显著差异,但干预组表现出更高的满意度和知识.

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