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验证BCIS CHIP评分的慢性全封闭性皮肤冠状动脉干预的验证

Athanasios Rempakos¹, Michaella Alexandrou¹, Deniz Mutlu¹

¹Minneapolis Heart Institute and Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

|April 17, 2024

概括

复杂高风险指标皮肤冠状动脉干预 (CHIP) 评分显示,在慢性全闭性 (CTO) PCI中,预测主要心脏或脑血管不良事件 (MACCE) 的能力很小. 较高的分数与增加的MACCE风险相关.

科学领域:

心脏病学心脏病学
干预心脏病学干预心脏病学
临床风险分层的临床风险分层

背景情况:

复杂高风险指示皮肤冠状动脉干预 (CHIP) 评分是为了识别高风险PCI病例和预测住院重大不良心脏或脑血管事件 (MACCE) 而开发的.
它在慢性全封闭 (CTO) 穿皮冠状动脉干预 (PCI) 的特定环境中的实用性需要验证.

研究的目的:

评估CHIP得分在接受CTO PCI的患者中的预测性表现和有效性.
在这个复杂的患者群体中确定CHIP得分值和MACCE发病率之间的关联.

主要方法:

从研究慢性全闭干预 (PROGRESS-CTO) 数据库的前性全球注册表中分析了8,341个CTO PCI程序的队列.
每位患者的CHIP得分被计算出来,并评估其与MACCE的相关性.
统计分析包括在不同的CHIP得分层中计算MACCE发生率,并确定预测能力曲线下的面积 (AUC).

主要成果:

CHIP得分与MACCE呈正相关性,发病率从0得分的0.6%增加到9+得分的8.7%.
每次CHIP得分增加1个单位,MACCE风险就会增加100%.
CHIP评分模型在CTO PCI队列中预测MACCE的AUC为0.63,表明预测能力适度.

结论:

在CTO PCI的背景下,CHIP得分对MACCE具有适度的预测能力.
虽然CHIP分数较高与风险增加有关,但为了在CTO干预中实现最佳应用,可能需要进一步细化.

关键词:

在CHIP分数中,我们获得了CHIP分数.慢性完全封闭症慢性完全封闭症主要不良心脏或脑血管事件通过皮肤进行冠状动脉干预.

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