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Updated: Jun 28, 2025

08:50
Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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概括
印度儿童患有慢性病 (CKD) 经历了肌肉力量和功能能力的降低. 接受脏移植的接受者 (KTR) 显示出最好的结果,而接受血液透析的患者有最严重的损伤.
科学领域:
- 儿科脏病学 儿科脏病学
- 运动生理学 运动生理学
- 康复医学 康复医学 康复医学
背景情况:
- 慢性病 (CKD) 显著影响儿童的健康,导致肌肉质量,力量和整体功能能力下降.
- 了解这些缺陷对于在儿科患者群体中开发有针对性的干预措施至关重要.
研究的目的:
- 评估和比较印度儿童在CKD不同阶段的功能能力和肌肉力量.
- 该研究评估了患有CKD I-V阶段的儿童,透析患者 (VD阶段) 和移植接受者 (KTR).
主要方法:
- 一项涉及60名印度儿童的横截面观察研究,分为三个组 (CKD I-V,VD,KTR).
- 功能能力和肌肉力量使用6分钟步行距离 (SMWD),定时地板站立测试 (TFTS) 和手握力 (HGS) 进行测量.
- 排除标准包括无法进行测试和最近的移植 (在6个月内).
主要成果:
- 移植接受者 (KTR) 与慢性病儿童和透析患者相比,表现出更高的功能能力和肌肉力量.
- 在各组中观察到SMWD,TFTS和HGS的显著差异 (p < 0.001).
- 估计的膜过率 (eGFR) 显示了SMWD和HGS的中度正相关性,以及TFTS的负相关性.
结论:
- 血液透析与印度儿童患有CKD肌肉强度和功能能力的最显著损害有关.
- 接受移植 (KTR) 的人表现出保存最好的身体功能,突出了移植的好处.
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