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Updated: Jun 27, 2026

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从患者自我报告中发现的trifluridine/tipiracil (TAS-102) 的发泄性:一个多中心,前性,观察性研究

Hironori Fujii1, Masami Tsuchiya2, Daichi Watanabe1,3

  • 1Department of Pharmacy, Gifu University Hospital, Gifu, Japan.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
|April 17, 2024
PubMed
概括

对于结肠直肠癌的trifluridine/tipiracil (TAS-102) 具有较低的吐率和高的患者满意度,这表明可能不需要统一的抗 Prophylaxis. 以前有化疗诱导的恶心和吐 (CINV) 的患者可能受益于预防性抗emetics.

关键词:
贝瓦西祖马布 (bevacizumab) 是一种药物.化疗引起的恶心和吐.三里丁/蒂皮拉西尔不能切除的结直肠癌.

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Genetic polymorphisms in drug targets have emerged as critical determinants of interindividual variability in drug response and toxicity. Pharmacogenomic investigations increasingly focus on identifying these variations to personalize and optimize therapeutic interventions. A drug target may be a receptor, enzyme, or signaling protein involved in pharmacologic responses or disease-related pathways. While early pharmacogenetic studies focused primarily on drug metabolism, current research...