身体脂肪预测移植患者的尿路感染:一项前性队列研究
Thaysa Sobral Antonelli1, Milena Dos Santos Mantovani1, Nyara Coelho de Carvalho1
1Medical School, São Paulo State University (Unesp), Botucatu, São Paulo, Brazil.
Journal of nephrology
|April 17, 2024
概括
腰围和内脏脂肪等肥胖指标可以预测移植后尿路感染 (UTI) 风险 (KTx). 身体质量指数不是一个可靠的预测指标,突出显示了体质成分分析对于UTI预防后KTx的重要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植免疫学 移植免疫学
- 传染性疾病 传染性疾病
背景情况:
- 越来越多的证据将肥胖与传染病联系在一起.
- 在移植 (KTx) 后,关于肥胖和尿路感染 (UTI) 的研究有限.
- 之前的研究使用体重指数 (BMI) 来定义肥胖,产生了相互矛盾的结果.
研究的目的:
- 研究移植受体体内体质与尿路感染风险之间的关联.
- 为了评估超出BMI的肥胖定义,利用生物电阻分析 (BIA).
主要方法:
- 一项单中心队列研究包括67名接受KTx.的患者.
- 收集的数据包括人口统计,临床因素和人类学.
- 生物电阻分析 (BIA) 测量了内脏脂肪面积,腰围和总脂肪质量.
- 尿路感染的发生在KTx后三个月内被监测.
主要成果:
- 尿路感染 (UTI) 在23.9%的患者中发生.
- 增加的腰围,内脏脂肪区域和总脂肪质量是KTx后尿路感染的显著预测因素.
- 高腰围 (男性>102厘米,女性>88厘米) 将尿路感染风险增加4.7倍.
- 体重指数 (BMI) 不能预测尿路感染风险.
结论:
- 腰围,内脏脂肪面积和BIA测量的总脂肪量是脏移植后三个月内尿路感染风险的关键预测指标.
- 这些身体成分指标提供了比单独的BMI更细致的了解与肥胖相关的尿路感染风险.
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